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Season 2 of ‘Best Medicine’ Brings Back Mermaids, Andrea Martin and a Blood Phobia Admission

A visit to the set of FOX's Best Medicine reveals 17 secrets, from a mermaid's fridge to the fate of Martin and Louisa.

By mitch·6 min read
A crew member walks through a dimly lit corridor labeled 'Port Wenn' on a television set.

Best Medicine, FOX’s medical dramedy, has returned, and it brought a mermaid, Andrea Martin, and a major character confession with it. After nearly six months off the air, the show came back for its Season 2 premiere on September 20. A recent set visit to the series’ sound stages in the Hudson Valley region revealed plenty of secrets the audience hasn’ was also seen.

The visit included in-person interviews with cast members Josh Charles, Jason Veasey, Stephen Spinella, Cree, and Didi Conn, plus EP Rodney Ferrell (Stick) and showrunner/EP Liz Tuccillo (Sex and the City, Divorce, Sweetbitter). The crew also toured the seafaring town’s sets, including The Salty Breeze, Aunt Sarah’s house, Louisa’s principal’s office, a newly built guest room, an under-construction beauty salon, Martin’s doctor’s office and home, and Charles’ trailer.

Here are the 17 behind-the-scenes secrets we learned from that trip.

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The Fridge Awards Have Been Won

One reporter admitted that peeking in a fridge is the first thing they do on a set visit. Aunt Sarah took the award for Best Fridge Interior of Best Medicine Season 2, with a bunch of apples and two bottles of wine inside. Martin’s fridge revealed a love of eggs, fruit, and olives.

The Best Fridge Exterior award has been given to Greg and George. Pictures of the performers and personal items hang on the fridge in The Salty Breeze’s kitchen, on the walls within the restaurant, and across every set visited. The care put into these details stands out. Cabinets and junk drawers are full. Graduate certificates are displayed. Reading glasses are scattered through Aunt Sarah’s house, with a pile of handwritten mail waiting by her door.

The Salty Breeze guest room and a beauty salon were both under construction as new locations for Season 2, with the aim of raising Best Medicine‘s set design to a higher level.

Martin and Louisa Are Still Endgame

Season 2 opens with Martin and Eden still together, and Louisa will have “sparks” with an upcoming guest star. But Charles told Decider that Martin has feelings for Louisa that he’s not always fully conscious of all the time, or he’s trying not to be.

The EPs agree. “No matter what happens, no matter if she gets another love interest, I don’t think any of us have to worry that there’s still something there,” Ferrell told Decider. “She’s patient with him, and listens, and doesn’t judge him. She’s actually okay with who he is. And I think that’s the kind of person he needs. Eden is not patient with him. Eden wants results. So I think Louisa services something for him that he actually needs.”

Tuccillo made a remark that included “There might be another love triangle that Louisa is involved with, because she can’t just be sitting around pining for Martin for a whole other season. But I think Louisa is the love of his life, and everything that he does besides that is just not right. He’s so damaged, it’s going to be a hard road to get them together. But they really are meant to be together.”.

Didi Conn Wants a Love Interest

After Geneva’s husband cheated on her with her sister, Didi Conn thinks it’s high time she finds love again. “Tell the writers!” she urged during the Season 2 chat.

Decider spoke with Tuccillo, who said that at the start of the season, Aunt Sarah’s attention centers on Martin, though “hopefully the last half she’s going to realize that it’s time for her to start thinking about love as well.”

Conn is perfectly content sharing scenes with her “long-lost sister” Annie Potts. “Annie and I have known each other kind of parallel, by living in LA, having similar friends, hearing about each other’s work… We belong to a mutual admiration society, my Annie and me.”

The Salty Breeze Menu Is Expensive

The Salty Breeze has confirmed its offerings, and they run from everyday small plates and salads all the way up to a $250 per person uni tasting menu. The restaurant is well known for its famous lobster rolls, and these dishes represent some of Port Wenn’s best eats.

The Cast Isn’t Begging for Karaoke Scenes

Several new singers step up to take the mic, while Josh Segarra keeps crushing karaoke in Season 2, but not every member of the Best Medicine cast shares their love for singing in public.

“Cree’s karaoke song, if she must — which she tries to avoid generally — is probably ‘Bust a Move,’ ” Cree told Decider. “Elaine’s would be ‘You Outta Know’ by Alanis Morissette. I think she would love the angst in that, the drama of it.”

Despite her iconic role in Grease, Conn said a big “No. Nope! Nope, no. I don’t think s”

How to Watch Best Medicine

For anyone just starting with the show, the first season can be found on Netflix. New episodes are currently rolling out on Hulu, which is the best way to catch up on them. The standard plan, which comes with ads, costs $11.99 a month. If you want to cut out the commercials, the ad-free tier runs $18.99 a month.

The Disney+ Bundles add Hulu to your subscription and come with a discount too. The lowest price begins at $12.99/month for ad-supported Disney+ and Hulu, while the most expensive bundle runs $32.99/month for Disney+, Hulu, and Max, all without ads.

The Verdict on the Set Visit

A walk through the fridge rooms, the menu boards, and the building work on set gave viewers a look at how the show is put together. The fridge awards brought laughter, the menu details raised curiosity, and the karaoke revelations were modest, but all three offered something worth seeing.

The biggest takeaway is that the show’s creators remain committed to Martin and Louisa. The love triangle is coming, but the endgame is not over. The EPs agree that Louisa is the love of Martin’s life, and the road to getting them together is hard but worth it.

A stop at the set brought some pleasant moments, though it did not amount to a thorough exploration. For those awaiting the next chapter, however, the visit provides a handful of answers — along with ample justification for staying tuned.

Key Facts Box

  • Season 2 premiere: September 20
  • Streaming platform: Hulu (new episodes); Netflix (Season 1)
  • Hulu basic price: $11.99/month (with ads)
  • Hulu ad-free price: $18.99/month
  • Disney+ Bundle price: $12.99/month for ad-supported, up to $32.99/month for ad-free
  • Uni tasting menu price: $250 per person
  • Guest star sparks with Louisa: Confirmed for later in the season

A return visit to the set shows that Best Medicine has not let its attention slip. From the fridges to the love triangles, the show continues to notice the small things that matter most.

Source material: “‘Best Medicine’ Is Back: 17 Secrets We Uncovered on the Season 2 Set,” Decider.

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